Mitochondrial dna dating who has shane west dating
The mitochondrial genes associated with cytochrome oxidase disrupts oxidative phosphorylation, causing a decrease in ATP production.
Researchers believe that impaired oxidative phosphorylation can lead to cell death in tissues that require large amounts of energy, such as the brain, muscles, and heart.
Cells that have high energy demands, such as those in the inner ear that are critical for hearing, are particularly sensitive to the effects of mitochondrial DNA damage.
This damage can irreversibly alter the function of the inner ear, leading to hearing loss.
As a result, reactive oxygen species easily damage mitochondrial DNA, causing cells to malfunction and ultimately to die.Although most DNA is packaged in chromosomes within the nucleus, mitochondria also have a small amount of their own DNA.This genetic material is known as mitochondrial DNA or mt DNA.Cell death in these and other sensitive tissues likely contribute to the features of cytochrome c oxidase deficiency.Most people with Kearns-Sayre syndrome have a single, large deletion of mitochondrial DNA.